The Kim Lab published a New Method for Arresting Drug Absorption in Microphysiological Devices

Martin Trapecar and his colleagues received a competitive “Maximizing Investigator’s Research Award” (MIRA) to help facilitate their research using multiorgan microphysiological systems to gain insight into a new class of immune cells.

Deok-Ho Kim, has been selected to receive the 2022 Engineer of the Year Award from the Korean-American Scientists and Engineers Association and the Korean Federation of Science and Technology Societies.

Our MPS center members David Gracias (lead author), Lena Smirnova and Thomas Hartung have recently published a new methodology in Sceince Advances that showcases the use of microelectrode arrays for electrophysiology recording from 400- to 600-μm-sized organoids for up to 4 weeks.

“Imagine if after a serious accident, your damaged facial bones could be replaced with tissue made by your own cells. Or if you could pop a pill that could reprogram your immune system to fight a chronic disease, freeing you from a lifetime of medications. While both prospects sound futuristic, scientists and engineers at Johns Hopkins and elsewhere are working toward these and other advances in tissue engineering. “

How these immobile cells generate the mechanical force needed to do their job is not fully understood. To unlock the secrets of this fluid transport process, a Johns Hopkins mechanical engineer has created a device that measures mechanical forces generated by both healthy and diseased kidney cells.

Proof-of-concept study in mice: scientists have successfully cultivated human muscle stem cells capable of renewing themselves and repairing muscle tissue damage.

The MPS (Microphysiological Systems) World Summit will bring together a global audience, including institutions (government, health foundations, charities), the academic research community (universities, research institutes), environmental and human toxicity researchers, the pharmaceutical and other industries (cosmetics, chemical, and food industries), medical centers and practitioners, patient associations, and policy makers and testing centers—in a series of global conferences to create roadmap for MPS technologies.